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The EC system is a recently characterised physiological system that includes receptors such as the CB1 receptor and it has been shown to play an important role in regulating body weight and in controlling energy balance, as well as glucose and lipid (or fat) metabolism. <h2>What is Zimulti used for?</h2> <p>Zimulti is used complementary to diet and exercise to treat obese or overweight patients who suffer from Type 2 diabetes and abnormal levels of fat in the blood.</p> <p>Sanofi argues that Zimulti can also prevent the risk of cardiovascular disease.</p> Patients with large waist circumference (102 cm in men and 88 cm in women) will mostly benefit from taking the drug. <h2>Does Zimulti also aid smoking cessation?</h2> <p>Zimulti has been studied by sanofi-aventis as an aid to smoking cessation based on studies for up to one year in over 6,500 smokers motivated to quit smoking.</p> Sanofi-aventis submitted a New Drug Application to the FDA, which in turn issued a non approvable letter for Zimulti for use in smoking cessation. An approvable letter was however issued for Zimulti for use in weight management. <h2>What are the side-effects of Zimulti?</h2> Side effects in the trial on Zimulti in obesity were vomiting and nausea, forcing about 19 percent of patients to leave the trial versus 13 percent of those who took placebo. <h2>What is the shelf life of the pills?</h2> The expiry date is mentioned on each blister. It is different for different batches. 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